3P281 Highly condenced GPCR Gene Cluster(Gene nion)
نویسندگان
چکیده
منابع مشابه
NION Highlights on HIV eradication in 2013
Virological remarks for HIV cure and eradication Latently HIV-1-infected cells are rare (especially in peripheral blood), but undistinguishable from uninfected cells, thus making their clearance extremely demanding. In addition, despite several efforts, a real consensus on mechanisms by which persistent HIV-1 reservoirs are established and maintained is still lacking, thus explaining why strate...
متن کاملBacMam: versatile gene delivery technology for GPCR assays.
BacMam viruses are modified baculoviruses that contain mammalian expression cassettes for viral gene delivery and transient expression in mammalian cells. They are easily, inexpensively, and rapidly generated and provide a versatile solution for G protein-coupled receptor (GPCR) cell-based assay development. Using BacMam technology, target gene expression levels are easily controlled and simult...
متن کاملOPI NION Highlights on HIV eradication in 2013
Virological remarks for HIV cure and eradication Latently HIV-1-infected cells are rare (especially in peripheral blood), but undistinguishable from uninfected cells, thus making their clearance extremely demanding. In addition, despite several efforts, a real consensus on mechanisms by which persistent HIV-1 reservoirs are established and maintained is still lacking, thus explaining why strate...
متن کاملPRED-GPCR: GPCR recognition and family classification server
The vast cell-surface receptor family of G-protein coupled receptors (GPCRs) is the focus of both academic and pharmaceutical research due to their key role in cell physiology along with their amenability to drug intervention. As the data flow rate from the various genome and proteome projects continues to grow, so does the need for fast, automated and reliable screening for new members of the ...
متن کاملGPCR-Targeted Library
Introduction Owing to historic inefficiency of mass random bioscreening, the current paradigm suggests that target-specific and pharmacokinetic properties of small molecule libraries should be addressed as early as possible in the discovery process. Computational medicinal chemistry can address this problem at the level of pre-synthetic library design. A number of advanced in silico methods hav...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Seibutsu Butsuri
سال: 2004
ISSN: 0582-4052,1347-4219
DOI: 10.2142/biophys.44.s260_1